(PubMed) Douaud G, Refsum H, de Jager CA, et al
Injections are also beneficial to those suffering from conditions such as rheumatoid arthritis, celiac disease and lupus, as these can prohibit the effective absorption of vitamin B12 found naturally within the diet

Composition Vitamin B12 (Cyanocobalamin or Methylcobalamin, depending on formulation) Lipotropic agents (varies by compounder, but commonly includes): Methionine Inositol Choline Benefits Supports fat metabolism and liver detoxification Enhances energy and focus Promotes red blood cell production May support weight management programs Format 10 ml vial Concentration varies by compounding pharmacy, but typically contains: Vitamin B12: 1000 mcg/ml Methionine, Inositol, Choline (varied doses, often 2550 mg/ml each) Dosage & Administration 1 ml per injection Administered intramuscularly (IM) Frequency: 23 times per week (as tolerated and per provider guidance) Storage Store refrigerated at 28 C Protect from light Do not freeze Notes Best used as part of a comprehensive wellness or weight management program (diet, exercise, lifestyle)
Temperature requirements Store reconstituted peptides in the refrigerator at 2-8 degrees Celsius (36-46 degrees Fahrenheit)
What are the B12 injection side effects
Gallbladder issues : Increased gallstone risk with rapid weight loss from GLP-1s